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Xiao,J.B.; Chen,X.Q.; Zhang,Y.W.; Jiang,X.Y.; Xu,M.. |
The cytotoxicity of three extracts (petroleum ether, ethyl acetate and n-butanol) from a plant used in folk medicine, Marchantia convoluta, to human non-small cell lung carcinoma (H1299) and liver carcinoma (HepG2) cell lines was tested. After 72-h incubation of lung and liver cancer cell cultures with varying concentrations of extracts (15 to 200 µg/mL), cytotoxicity was determined by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay and reported in terms of cell viability. The extracts that showed a significant cytotoxicity were subjected to gas chromatography-mass spectrometry analysis to identify the components. The ethyl acetate, but not the petroleum ether or n-butanol extract, had a significant cytotoxicity against lung and... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Marchantia convoluta extract; Cytotoxicity assay; HepG2 and H1299 carcinoma cell lines; Phytol; Caryophyllene oxide. |
Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000600005 |
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Moreno,Paulo Roberto H.; Lima,Marcos Enoque Leite; Sobral,Marcos; Young,Maria Cláudia Marx; Cordeiro,Inês; Apel,Miriam Anders; Limberger,Renata Pereira; Henriques,Amélia Teresinha. |
Eugenia brasiliensis Lam. is a variable species concerning fruit colour, with three recognized varieties. However, the definition of varieties is not easy for Myrtaceae species and not widely accepted. Two fruit colour varieties (purple and yellow) of E. brasiliensis had their essential oil composition analysed in order to give support to the existence of varieties for this species. Although, the major components in the leaf oil are the same monoterpenes for both varieties, alpha-pinene, beta-pinene and 1,8-cineol, the purple fruit variety accumulates more oxygenated sesquiterpenes (33.9%) than the one with yellow fruits (3.8%). The major differences occurred in purple fruits that present as major components caryophyllene oxide (22.2%) and alpha-cadinol... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Myrtaceae; Chemotypes; Terpenes; Pinenes; Caryophyllene oxide. |
Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162007000400014 |
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